DR. SUJIT CHOWDHARY

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Case Study- Pre & Post (Botox +Anti Ach+CIC) cystometry 6mo

Introduction

  • 15 year old girl from Kathmandu
  • B/L VUR, rec UTI, busiest urology unit
  • B/L ureteric reimplantation, May 2012
  • bladder dehiscence, pelvic urinoma
  • SPC, managed conservatively
  • 2 months later, UTI persisting
  • Difficulty in voiding, Indwelling catheter
  • Rising S. Creatinine , 2mg/dl
  • Referred to our unit
Robotic augmentation ileocystoplasty

USG & DMSA renal scan high PVR, L kidney gone!!


USG DMSA renal scan     DMSA renal scan

Urodynamic study

  • USG, VCUG, VUD , Cystoscopyu
  • MR LS spine normal
  • B/L VUR, High PVR
  • Pdet >30cm at 30% EBC
  • Neuropathic bladder,LS MRI n
  • Non Neuropathic, Extravesical reimplant
  • CIC + oxybutynin
urodynamic study

Pre & Post (Botox +Anti Ach+CIC) cystometry 6mo


cystometry pre     cystometry post

1 year later…

  • CIC + oxybutynin
  • UTI persisting
  • Progressive rise in S creatinine
  • New scars on DMSA scan
  • Inj. Botox 10mg/kg
CIC-1 year later

Pre & post inj. Botox (1 month) cystometry


Botox pre     Botox-post

Pre & Post (Botox +Anti Ach+CIC) cystometry 6mo


cystometry pre     cystometry post

CIC + AntiACh + Botox

  • Post Botox transient relief
  • Rising S. creatinine
  • Stable scars on DMSA
  • Cystometry worsened again
  • Augmentation ileocystoplasty
  • Ureteric reimplant
  • Open/robotic
AntiACh

3 months post augmentation S creat & UDS


AntiACh     UDS post

Post Botox-Post Augmentation 10y


Botox Post Augmentation     Post Botox Post Augmentation

Pre-Post Augment Cystometry:9y fu Case 2


9y-fu-case-2      9y-fu-case 2 post

Ten years later ….


10-years-later      10-years-later

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