Case Study- Pre & Post (Botox +Anti Ach+CIC) cystometry 6mo
Introduction
15 year old girl from Kathmandu
B/L VUR, rec UTI, busiest urology unit
B/L ureteric reimplantation, May 2012
bladder dehiscence, pelvic urinoma
SPC, managed conservatively
2 months later, UTI persisting
Difficulty in voiding, Indwelling catheter
Rising S. Creatinine , 2mg/dl
Referred to our unit
USG & DMSA renal scan
high PVR, L kidney gone!!
Urodynamic study
USG, VCUG, VUD , Cystoscopyu
MR LS spine normal
B/L VUR, High PVR
Pdet >30cm at 30% EBC
Neuropathic bladder,LS MRI n
Non Neuropathic, Extravesical reimplant
CIC + oxybutynin
Pre & Post (Botox +Anti Ach+CIC) cystometry 6mo
1 year later…
CIC + oxybutynin
UTI persisting
Progressive rise in S creatinine
New scars on DMSA scan
Inj. Botox 10mg/kg
Pre & post inj. Botox (1 month) cystometry
Pre & Post (Botox +Anti Ach+CIC) cystometry 6mo
CIC + AntiACh + Botox
Post Botox transient relief
Rising S. creatinine
Stable scars on DMSA
Cystometry worsened again
Augmentation ileocystoplasty
Ureteric reimplant
Open/robotic
3 months post augmentation S creat & UDS
Post Botox-Post Augmentation 10y
Pre-Post Augment Cystometry:9y fu Case 2